Quick Answer
The safest way to remove facial hair while on Accutane (isotretinoin) is to trim it or shave gently, ideally with an electric razor or trimmer and a fragrance-free moisturizer. Avoid waxing, sugaring and laser hair removal during treatment and, per the drug’s labeling and dermatology guidance, for at least six months after your last dose, because isotretinoin makes skin fragile and slow to heal.
Key Takeaways
- Isotretinoin thins and dries the skin, so pulling or heating it can tear the surface, scar or cause dark patches.
- Waxing and skin resurfacing should be avoided during treatment and for at least six months afterward.
- Electric trimmers and careful shaving are the gentlest options for most people.
- Threading, epilators, depilatory creams and bleach can irritate fragile skin; ask your dermatologist first.
- Ask your prescriber before laser hair removal, even after treatment ends.
Isotretinoin, sold under brand names such as Absorica, Amnesteem, Claravis and Zenatane (Accutane is the original brand name), is highly effective for severe acne. It also changes how your skin behaves for months. Hair removal routines that were fine before treatment can suddenly leave raw patches, so this guide covers what is safe, what to skip and how to protect your skin until it recovers.

Why Is Hair Removal Risky on Accutane?
Isotretinoin shrinks oil glands and speeds up the turnover of skin cells. The result is clearer skin, but also skin that is drier, thinner and slower to heal. Common side effects include dry, peeling lips, dry facial skin, increased sun sensitivity and easier bruising or tearing of the skin.
When hot wax or sugar paste is pulled off, it can strip away the top layer of skin along with the hair, leaving raw, weeping patches. These wounds heal slowly on isotretinoin and can scar or leave dark marks, especially on medium to dark skin tones. Laser and other heat- or abrasion-based treatments raise similar concerns, which is why the prescribing information and the American Academy of Dermatology advise caution.
Which Hair Removal Methods Are Safe on Accutane?
| Method | During isotretinoin | Why |
|---|---|---|
| Electric trimmer or clipper | Generally the safest choice | Cuts hair above the skin without scraping it |
| Electric razor (foil shaver) | Usually fine with care | Less skin contact and fewer nicks than a blade |
| Manual razor | Possible with care | Use a sharp blade and gentle technique; nicks heal slowly |
| Tweezing a few stray hairs | Use sparingly | Low risk for single hairs; avoid on broken skin |
| Threading | Ask your dermatologist | Friction and pulling can irritate or break fragile skin |
| Epilator | Avoid | Pulls many hairs at once and can tear skin |
| Depilatory creams | Avoid unless approved | Strong chemicals can burn dry, sensitive skin |
| Facial bleach | Avoid unless approved | Can irritate and sting compromised skin |
| Waxing or sugaring | Avoid during and for at least 6 months after | Can remove the top layer of skin and cause scarring |
| Laser or IPL hair removal | Avoid; ask your prescriber about timing after | Labeling advises caution due to risk of scarring |

How Do You Shave or Trim Facial Hair Safely on Accutane?
Step 1: Choose the Gentlest Tool
An electric trimmer is the lowest-risk option because the blades do not touch the skin directly. An electric foil shaver is next. If you prefer a manual razor, use a fresh, sharp blade; dull blades drag and cause more nicks.
Step 2: Soften the Hair
Shave after a lukewarm shower or hold a warm, damp cloth on the area for a minute or two. Avoid hot water, which dries out the skin further.
Step 3: Use a Fragrance-Free Shaving Product
Apply a fragrance-free shaving cream or gel for sensitive skin, or a thin layer of your gentle moisturizer if you use an electric shaver that allows wet shaving. Avoid products containing alcohol, menthol, strong fragrances or exfoliating acids.
Step 4: Shave With Light Pressure and the Grain
Use short, light strokes in the direction of hair growth and avoid going over the same spot repeatedly. Do not stretch the skin hard. Shave around any active pimples or dry, cracked areas rather than over them.
Step 5: Rinse, Pat Dry and Moisturize
Rinse with cool or lukewarm water, pat dry with a clean towel and immediately apply a fragrance-free moisturizer or a thin layer of petroleum jelly. Skip aftershaves with alcohol. Use broad-spectrum SPF 30 or higher sunscreen during the day.
Step 6: Keep Tools Clean
Rinse blades and trimmer heads after each use and let them dry. Replace razor blades often and never share them, since small cuts on fragile skin can let bacteria in.

Can You Get Laser Hair Removal While on Accutane?
The longstanding guidance in isotretinoin labeling is to avoid laser procedures and other skin resurfacing treatments during treatment and for at least six months afterward because of a risk of scarring. Some recent studies have suggested certain laser treatments may be safer than once thought, and some dermatologists are revising their approach case by case. Because the decision depends on your skin, the type of laser and your treatment history, do not book laser hair removal on your own. Ask the dermatologist who prescribes your isotretinoin, and tell any laser clinic that you are taking or have recently taken it.
Safety: Always tell estheticians, laser technicians and spa staff that you are on isotretinoin or have taken it in the past six months. Reputable providers will postpone waxing, chemical peels, microdermabrasion and laser treatments.
What If You Get Irritation or a Cut?
Minor nicks usually stop bleeding with gentle pressure from a clean tissue for a few minutes. Keep the area clean and covered with petroleum jelly while it heals. If you develop razor bumps, pause shaving for a few days and moisturize. Contact your dermatologist if you notice skin that is raw, weeping, crusted with yellow scabs, increasingly painful or red, or any cut that is slow to heal, since these can signal infection or a reaction that needs treatment.
Managing Unwanted Facial Hair Long Term
If facial hair is thick or bothers you a lot, plan ahead with your dermatologist. Once you have been off isotretinoin long enough and your skin has recovered, options such as laser hair removal, electrolysis or prescription creams like eflornithine may be discussed. If you notice new or increasing coarse facial hair, especially with irregular periods or acne, mention it, because a hormonal condition such as PCOS can cause both acne and excess hair growth.
For more on caring for acne-prone skin during and after treatment, see our guides on reducing pimples with a gentle routine and controlling oily skin.

Other Skin Care Tips While on Isotretinoin
- Use a gentle, non-foaming cleanser and a rich, fragrance-free moisturizer twice a day.
- Apply lip balm often; dry, cracked lips are one of the most common side effects.
- Wear sunscreen daily and avoid tanning beds.
- Pause retinoid creams, scrubs and exfoliating acids unless your dermatologist says otherwise.
- Follow all iPLEDGE program requirements and attend your monthly appointments.
Medical disclaimer: This article is for general information and is not medical advice. Talk to your prescribing dermatologist before using any hair removal method, cosmetic procedure or new skin product while taking isotretinoin or in the months after you stop.
Frequently Asked Questions
Can I wax my eyebrows while on Accutane?
No. Isotretinoin labeling and dermatologists advise avoiding waxing during treatment and for at least six months after your last dose because it can pull off the top layer of skin and cause scarring. Trimming or carefully tweezing a few stray hairs is a safer option for brows.
Is threading safe on Accutane?
Threading is gentler than waxing but still involves friction and pulling on fragile skin, which can cause irritation or small tears. Opinions vary among dermatologists, so ask your prescriber before booking. If approved, tell the threader you are on isotretinoin and avoid any irritated areas.
Can I use Nair or other hair removal creams on Accutane?
Depilatory creams contain strong chemicals that can burn or severely irritate the dry, sensitive skin caused by isotretinoin. Most dermatologists recommend avoiding them during treatment. If you want to use one, ask your dermatologist first and always do a patch test.
How long after Accutane can I get laser hair removal?
Traditional guidance is to wait at least six months after your last dose of isotretinoin before laser hair removal or skin resurfacing. Some newer research suggests certain lasers may be safe sooner in selected cases, but timing should be decided by your dermatologist based on your skin and history.
Is it safe to shave on Accutane?
Yes, shaving is generally considered one of the safest options. Use an electric trimmer or shaver if possible, or a sharp manual razor with fragrance-free gel and light pressure. Moisturize right after, and avoid shaving over active pimples or cracked skin.



